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A Phase II, Open-Label, Randomized, Multicenter Trial of Pazopanib (GW786034) in Combination with Lapatinib (GW572016) Compared to Pazopanib Monotherapy and Lapatinib Monotherapy in Subjects with FIGO Stage IVB or Recurrent or Persistent Cervical Cancer with Zero or One Prior Chemotherapy Regimen for Advanced/Recurrent Disease.

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Trial Profile

A Phase II, Open-Label, Randomized, Multicenter Trial of Pazopanib (GW786034) in Combination with Lapatinib (GW572016) Compared to Pazopanib Monotherapy and Lapatinib Monotherapy in Subjects with FIGO Stage IVB or Recurrent or Persistent Cervical Cancer with Zero or One Prior Chemotherapy Regimen for Advanced/Recurrent Disease.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 05 Oct 2021

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At a glance

  • Drugs Lapatinib (Primary) ; Pazopanib (Primary)
  • Indications Carcinoma; Cervical cancer; Squamous cell cancer; Uterine cancer
  • Focus Therapeutic Use
  • Sponsors GlaxoSmithKline
  • Most Recent Events

    • 23 Jun 2012 Planned number of patients changed from 180 to 210 as reported by European Clinical Trials Database.
    • 11 Mar 2011 Planned end date changed from Sep 2010 to May 2011 as reported by ClinicalTrials.gov.
    • 02 Jun 2009 Final results were presented at ASCO 2009.
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