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A Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Safety and Antiretroviral Activity of MK0518 in Combination With an Optimized Background Therapy (OBT), Versus Optimized Background Therapy Alone, in HIV-Infected Patients With Documented Resistance to at Least 1 Drug.

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A Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Safety and Antiretroviral Activity of MK0518 in Combination With an Optimized Background Therapy (OBT), Versus Optimized Background Therapy Alone, in HIV-Infected Patients With Documented Resistance to at Least 1 Drug.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 31 May 2022

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At a glance

  • Drugs Raltegravir (Primary) ; Antiretrovirals
  • Indications HIV-1 infections
  • Focus Registrational; Therapeutic Use
  • Acronyms BENCHMRK-2
  • Sponsors Merck & Co; Merck Sharp & Dohme

    • Most Recent Events

    • 12 May 2022 A systematic literature review was conducted to identify trials with designs and populations comparable to BRIGHTE, results published in the Clinical Therapeutics
    • 27 Jul 2012 5-Year results from a pooled analysis of BENCHMRK I and II presented at the 19th International AIDS Conference.
    • 22 Jul 2012 Five-year results have been presented at the 19th International AIDS Conference according to a Merck media release.

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