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A Phase III Study Comparing Imatinib Standard Dose (400 mg/Day) Versus Imatinib High Dose (800 mg/Day) in the Treatment of Newly Diagnosed High Risk Chronic Myeloid Leukemia in Chronic Phase

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Trial Profile

A Phase III Study Comparing Imatinib Standard Dose (400 mg/Day) Versus Imatinib High Dose (800 mg/Day) in the Treatment of Newly Diagnosed High Risk Chronic Myeloid Leukemia in Chronic Phase

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 10 Nov 2021

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At a glance

  • Drugs Imatinib (Primary)
  • Indications Chronic myeloid leukaemia
  • Focus Registrational; Therapeutic Use
  • Acronyms TOPS
  • Most Recent Events

    • 04 Dec 2018 Results comparing the prognostic value of ELTS and Sokal scores in a cohort of CML patients treated frontline with tyrosine kinase inhibitors presented at the 60th Annual Meeting and Exposition of the American Society of Hematology
    • 01 Aug 2017 Results of long term outcomes (n=559) of 3 studies (CML021, CML022, CML023) published in the American Journal of Hematology.
    • 08 Dec 2015 Long term analysis of 3 trials (n=559) presented at the 57th Annual Meeting and Exposition of the American Society of Hematology

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