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A phase I, randomized, two-period, single-center study to assess the effect of CYP2D6 and CYP2C19 inhibitors on a single oral dose of AV650 [tolperisone] (300 mg) in healthy subjects

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A phase I, randomized, two-period, single-center study to assess the effect of CYP2D6 and CYP2C19 inhibitors on a single oral dose of AV650 [tolperisone] (300 mg) in healthy subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 17 Sep 2021

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At a glance

  • Drugs Tolperisone (Primary) ; Fluvoxamine; Paroxetine
  • Indications Anxiety disorders; Back pain; Depressive disorders; Irritable bowel syndrome; Obsessive-compulsive disorders; Social phobia
  • Focus Pharmacokinetics
  • Sponsors Avigen

    • Most Recent Events

    • 18 Sep 2007 Status changed from recruiting to completed.
    • 16 Apr 2007 New trial record.

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