A randomized, open-label, 3-period crossover study to evaluate the effect of multiple doses of DVS SR [desvenlafaxine sustained release] and paroxetine on the CYP2D6 biotransformation of codeine to morphine in healthy subjects
Phase of Trial: Phase I
Latest Information Update: 20 May 2009
At a glance
- Drugs Codeine; Desvenlafaxine; Paroxetine
- Indications Anxiety; Depression; Depressive disorders; Pain
- Focus Pharmacokinetics
- Sponsors Wyeth
- 20 May 2009 Results presented at the 162nd Annual Meeting of the American Psychiatric Association (APA 2009).
- 17 Apr 2007 New trial record.