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A phase 2b, randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy, safety, PK [pharmacokinetics], and PD [pharmacodynamics] of BG9924 [baminercept] when given in combo [combination] with MTX [methotrexate] to subjects with active RA [rheumatoid arthritis] who have had an inadequate response to anti-TNF [tumour necrosis factor]

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Trial Profile

A phase 2b, randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy, safety, PK [pharmacokinetics], and PD [pharmacodynamics] of BG9924 [baminercept] when given in combo [combination] with MTX [methotrexate] to subjects with active RA [rheumatoid arthritis] who have had an inadequate response to anti-TNF [tumour necrosis factor]

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 10 Nov 2021

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At a glance

  • Drugs Baminercept (Primary)
  • Indications Rheumatoid arthritis
  • Focus Therapeutic Use
  • Sponsors Biogen
  • Most Recent Events

    • 06 Nov 2008 Status changed from recruiting to discontinued.
    • 16 Oct 2008 Planned end date changed from Sep 2008 to Dec 2008, as reported by ClinicalTrials.gov.
    • 10 Oct 2008 Primary endpoint 'American College of Rheumatology 50% response criteria' has not been met during a preliminary analysis.

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