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A randomized phase II trial of concurrent chemoradiation with cetuximab (Erbitux), 5 fluorouracil, hydroxyurea [hydroxycarbamide], and twice-daily radiation (CetuxFHX) versus cetuximab (Erbitux), cisplatin and accelerated radiation with concomitant boost (CetuxPX) after induction chemotherapy in patients with locally advanced head and neck cancer

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Trial Profile

A randomized phase II trial of concurrent chemoradiation with cetuximab (Erbitux), 5 fluorouracil, hydroxyurea [hydroxycarbamide], and twice-daily radiation (CetuxFHX) versus cetuximab (Erbitux), cisplatin and accelerated radiation with concomitant boost (CetuxPX) after induction chemotherapy in patients with locally advanced head and neck cancer

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 11 Oct 2019

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At a glance

  • Drugs Cetuximab (Primary) ; Cisplatin; Fluorouracil; Hydroxycarbamide
  • Indications Head and neck cancer
  • Focus Therapeutic Use
  • Acronyms EPIC
  • Most Recent Events

    • 20 Sep 2019 Status changed from active, no longer recruiting to completed.
    • 09 Oct 2012 Planned End Date changed from 1 Jul 2012 to 1 Nov 2012 as reported by ClinicalTrials.gov.
    • 07 Jun 2011 Results were presented at the 47th Annual Meeting of the American Society of Clinical Oncology.

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