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Preservation of renal function in liver transplant recipients with Certican therapy: PROTECT study A twelve-month, multicenter, randomized, open-label study of safety, tolerability and efficacy of Certican-based regimen versus calcineurin inhibitor-based regimen in de novo liver transplant recipients

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Preservation of renal function in liver transplant recipients with Certican therapy: PROTECT study A twelve-month, multicenter, randomized, open-label study of safety, tolerability and efficacy of Certican-based regimen versus calcineurin inhibitor-based regimen in de novo liver transplant recipients

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 06 Apr 2022

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At a glance

  • Drugs Everolimus (Primary) ; Basiliximab; Ciclosporin; Tacrolimus
  • Indications Liver transplant rejection
  • Focus Adverse reactions; Registrational
  • Acronyms PROTECT
  • Sponsors Novartis Pharma

    • Most Recent Events

    • 24 Oct 2017 Pooled results assessing long-term clinical outcomes in patients with autoimmune liver diseases from two phase III trials (H2304 and PROTECT; n=23) presented at The Liver Meeting 2017: 68th Annual Meeting of the American Association for the Study of Liver Diseases
    • 10 May 2016 Results of a five year follow up study (n=81) published in the Clinical Transplantation.
    • 17 Feb 2014 Added related profile

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