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A double-blind, randomised, placebo controlled, single dose, two-period crossover study to investigate the therapeutic potential of the TRPV1 antagonist SB-705498 in treatment of subjects with rectal hypersensitivity including irritable bowel syndrome.

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Trial Profile

A double-blind, randomised, placebo controlled, single dose, two-period crossover study to investigate the therapeutic potential of the TRPV1 antagonist SB-705498 in treatment of subjects with rectal hypersensitivity including irritable bowel syndrome.

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 15 Jul 2023

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At a glance

  • Drugs GSK 705498 (Primary)
  • Indications Irritable bowel syndrome
  • Focus Therapeutic Use
  • Sponsors GlaxoSmithKline; GSK
  • Most Recent Events

    • 27 Jul 2020 This trial is completed (Global End Date: 22 Feb 2007), according to European Clinical Trials Database record.
    • 08 Nov 2007 Patient numbers amended from 42 to 1.
    • 08 Nov 2007 Status changed from recruiting to discontinued.

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