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A Phase II, Double Blind, Placebo Controlled, Randomised Study to Assess the Efficacy and Safety of 2 Doses of ZACTIMA™(ZD6474) in Combination With FOLFIRI vs FOLFIRI Alone for the Treatment of Colorectal Cancer in Patients Who Have Failed Therapy With an Oxaliplatin and Fluoropyrimidine Containing Regimen

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A Phase II, Double Blind, Placebo Controlled, Randomised Study to Assess the Efficacy and Safety of 2 Doses of ZACTIMA™(ZD6474) in Combination With FOLFIRI vs FOLFIRI Alone for the Treatment of Colorectal Cancer in Patients Who Have Failed Therapy With an Oxaliplatin and Fluoropyrimidine Containing Regimen

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 29 Jul 2019

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At a glance

  • Drugs Vandetanib (Primary) ; Fluorouracil; Folinic acid; Irinotecan
  • Indications Colorectal cancer
  • Focus Therapeutic Use
  • Sponsors Genzyme Corporation

    • Most Recent Events

    • 14 Apr 2009 Planned end date (May 2009) added as reported by ClinicalTrials.gov.
    • 17 Jan 2009 Primary endpoint results presented at ASCO-GCS
    • 11 May 2008 The actual completion date for this trial is Apr 2008

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