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A Phase II, Single-arm, Open-label Study of Trastuzumab-MCC-DM1 Administered Intravenously to Patients With HER2-Positive Metastatic Breast Cancer Who Have Progressed While Receiving HER2-Directed Therapy

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A Phase II, Single-arm, Open-label Study of Trastuzumab-MCC-DM1 Administered Intravenously to Patients With HER2-Positive Metastatic Breast Cancer Who Have Progressed While Receiving HER2-Directed Therapy

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 10 Nov 2021

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At a glance

  • Drugs Trastuzumab emtansine (Primary)
  • Indications Advanced breast cancer; HER2 positive breast cancer
  • Focus Registrational; Therapeutic Use
  • Sponsors Genentech

    • Most Recent Events

    • 07 Jan 2020 Results of an individual patient-level data pooled analysis of trials testing T-DM1 in the advanced setting investigating T-DM1-induced cardiotoxicity, with a focus on the incidence of CEs, clinical presentation of CEs, impact on treatment continuity, reversibility as well as in any potential risk factors that could aid in patient selection and follow-up published in the European Journal of Cancer
    • 09 Jun 2009 Status changed from active, no longer recruiting to completed.
    • 31 May 2009 Results have been presented at the 2009 Annual Meeting of the American Society of Clinical Oncology (ASCO), according to an Immunogen media release.

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