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A Phase 2 Study to Evaluate the Safety and Efficacy of Weekly Doses of Marqibo (vincristine sulfate liposomes injection) in Adult Patients with Philadelphia Chromosome-negative Acute Lymphoblastic Leukemia (ALL) in Second Relapse or Adult Patients with Philadelphia Chromosome-negative ALL Who Failed Two Treatment Lines of Anti-leukemia Chemotherapy (HBS407).

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Trial Profile

A Phase 2 Study to Evaluate the Safety and Efficacy of Weekly Doses of Marqibo (vincristine sulfate liposomes injection) in Adult Patients with Philadelphia Chromosome-negative Acute Lymphoblastic Leukemia (ALL) in Second Relapse or Adult Patients with Philadelphia Chromosome-negative ALL Who Failed Two Treatment Lines of Anti-leukemia Chemotherapy (HBS407).

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 10 Nov 2021

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At a glance

  • Drugs Vincristine (Primary)
  • Indications Precursor cell lymphoblastic leukaemia-lymphoma
  • Focus Registrational; Therapeutic Use
  • Acronyms rALLy
  • Sponsors Spectrum Pharmaceuticals; Talon Therapeutics

    • Most Recent Events

    • 08 Dec 2015 Results of post-hoc analysis (n=44) presented at the 57th Annual Meeting and Exposition of the American Society of Hematology
    • 06 Jun 2011 Results have been presented at ASCO-2011 according to a Talon Therapeutics media release. Results were also summarised in the media release.
    • 29 Nov 2010 According to a company media release, Hana Biosciences presented results from this trial at ASH (abstract A2142).

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