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A phase II open-label, non-comparative, international, multicentre study to assess the efficacy and safety of KU 0059436 [KU 59436] given orally twice daily in patients with advanced BRCA1 or BRCA2 associated ovarian cancer

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Trial Profile

A phase II open-label, non-comparative, international, multicentre study to assess the efficacy and safety of KU 0059436 [KU 59436] given orally twice daily in patients with advanced BRCA1 or BRCA2 associated ovarian cancer

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 10 Nov 2021

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At a glance

  • Drugs Olaparib (Primary)
  • Indications Carcinoma; Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • Focus Therapeutic Use
  • Acronyms ICEBERG-2
  • Sponsors AstraZeneca; KuDOS Pharmaceuticals
  • Most Recent Events

    • 14 Sep 2017 Status changed from active, no longer recruiting to completed.
    • 27 Dec 2016 Planned End Date changed from 1 Dec 2016 to 1 Dec 2017.
    • 08 Mar 2016 Results (pooled analysis of this and five other studies (n = 300) assessing olaparib monotherapy in patients with advanced relapsed BRCA1/2 ovarian cancer) published in the Annals of Oncology.
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