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A multicentre double-blind, randomized parallel group study to evaluate the efficacy safety and tolerability of ezetimibe/simvastatin 10/40mg, atorvastatin 40mg, and rosuvastatin 10mg to Achieve an LDL-C [low-density lipoprotein-Cholesterol] Level of less than 2mmol/L in patients with established cardio vascular disease (CVD) or at 'High Risk' of Developing CVD Currently Treated With Simvastatin 40mg and With a Fasting LDL-C 2 Mmol/L

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Trial Profile

A multicentre double-blind, randomized parallel group study to evaluate the efficacy safety and tolerability of ezetimibe/simvastatin 10/40mg, atorvastatin 40mg, and rosuvastatin 10mg to Achieve an LDL-C [low-density lipoprotein-Cholesterol] Level of less than 2mmol/L in patients with established cardio vascular disease (CVD) or at 'High Risk' of Developing CVD Currently Treated With Simvastatin 40mg and With a Fasting LDL-C 2 Mmol/L

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 05 May 2022

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At a glance

  • Drugs Ezetimibe/simvastatin (Primary) ; Atorvastatin; Rosuvastatin
  • Indications Cardiovascular disorders
  • Focus Therapeutic Use
  • Sponsors Merck & Co; Organon

    • Most Recent Events

    • 30 Jul 2019 New source Identified and Integrated as per European Clinical Trials Database (EudraCT) record.
    • 29 Aug 2009 Results presented at ESC Congress 2009: Annual Congress of the European Society of Cardiology.
    • 29 Aug 2009 Primary endpoint 'Target achievement rate' has been met, according to results presented at ESC Congress 2009: Annual Congress of the European Society of Cardiology.

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