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An International, Double-blind, Parallel-group, Placebo-controlled, Randomized Study: Evaluation of the Efficacy and Safety of Brivaracetam in Subjects (≥ 16 to 70 Years Old) With Partial Onset Seizures

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Trial Profile

An International, Double-blind, Parallel-group, Placebo-controlled, Randomized Study: Evaluation of the Efficacy and Safety of Brivaracetam in Subjects (≥ 16 to 70 Years Old) With Partial Onset Seizures

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 24 May 2022

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At a glance

  • Drugs Brivaracetam (Primary)
  • Indications Partial epilepsies; Seizures
  • Focus Registrational; Therapeutic Use
  • Sponsors UCB; UCB Pharma Inc

    • Most Recent Events

    • 17 May 2022 Results of pooled post hoc (N01252/NCT00490035, N01253/NCT00464269, and N01358/NCT01261325 studies) analysis published in the Epilepsia
    • 26 Apr 2022 Results of post hoc analysis of 3 phase III trials (N01252 [NCT00490035], N01253 [NCT00464269], N01358 [NCT01261325]) assessing the time-course of treatment-emergent adverse events (TEAEs) potentially associated with behavioral disorders (BAEs) in adults with focal seizures during adjunctive brivaracetam (BRV) treatment presented at the 74th Annual Meeting of the American Academy of Neurology 2022
    • 01 Sep 2021 Results of post-hoc analysis of 3 studies (N01252/NCT00490035, N01253/NCT004642 69, N01358/NCT01261325) assessing tolerability and efficacy of brivaracetam (BRV) in patients on 1 or 2 concomitant antiepileptic drugs (AEDs) and in patients on 1 specific concomitant AED, presented at the 34th International Epilepsy Congress.

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