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A Randomized, Double-Blind, Parallel-Group, Cross-Over, 4-Period, 4 Treatment, Within-Subject Placebo-Controlled Study to Assess the Reno-Protective Effect of Renin Inhibition With Aliskiren as an Alternative to Irbesartan in Type 2 Patients With Incipient/Overt Diabetic Nephropathy

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A Randomized, Double-Blind, Parallel-Group, Cross-Over, 4-Period, 4 Treatment, Within-Subject Placebo-Controlled Study to Assess the Reno-Protective Effect of Renin Inhibition With Aliskiren as an Alternative to Irbesartan in Type 2 Patients With Incipient/Overt Diabetic Nephropathy

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 10 Nov 2021

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At a glance

  • Drugs Aliskiren (Primary) ; Irbesartan
  • Indications Diabetic nephropathies; Hypertension; Proteinuria; Type 2 diabetes mellitus
  • Focus Biomarker; Pharmacodynamics; Therapeutic Use
  • Sponsors Novartis

    • Most Recent Events

    • 13 Oct 2009 Actual end date (Nov 2007) added as reported by ClinicalTrials.gov.
    • 01 Oct 2009 Results were published in Diabetes Care.
    • 07 Sep 2008 Results have been presented at EASD 2008. Primary endpoint met.

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