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A randomized, multicenter, double blinded, phase IV study comparing the safety and efficacy of Pegasys [Peginterferon alfa-2a] 180 microg plus Copegus [ribavirin] 1000 or 1200 mg to the currently approved combination of Pegasys 180 microg plus Copegus 800 mg in interferon-naive patients with chronic hepatitis C genotype 1 virus infection co-infected with HIV-1

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A randomized, multicenter, double blinded, phase IV study comparing the safety and efficacy of Pegasys [Peginterferon alfa-2a] 180 microg plus Copegus [ribavirin] 1000 or 1200 mg to the currently approved combination of Pegasys 180 microg plus Copegus 800 mg in interferon-naive patients with chronic hepatitis C genotype 1 virus infection co-infected with HIV-1

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 10 Nov 2021

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At a glance

  • Drugs Peginterferon alfa-2a (Primary) ; Ribavirin (Primary)
  • Indications Hepatitis C
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms PARADIGM
  • Sponsors Roche

    • Most Recent Events

    • 14 Apr 2010 Results presented at the 45th Annual Meeting of the European Association for the Study of the Liver.
    • 03 Feb 2010 Planned number of patients changed from 400 to 415 as reported by ClinicalTrials.gov.
    • 18 Nov 2009 Status changed from active, no longer recruiting to completed as reported by Roche.

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