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Double blind, randomised, placebo controlled study to evaluate the safety, tolerability and pharmacokinetics of single doses of GSK1014802 and the effect of single doses of GSK1014802 or lamotrigine on resting motor threshold in healthy volunteers.

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Trial Profile

Double blind, randomised, placebo controlled study to evaluate the safety, tolerability and pharmacokinetics of single doses of GSK1014802 and the effect of single doses of GSK1014802 or lamotrigine on resting motor threshold in healthy volunteers.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 06 Sep 2023

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At a glance

  • Drugs Vixotrigine (Primary) ; Lamotrigine
  • Indications Absence epilepsy; Bipolar disorders; Depressive disorders; Lennox-Gastaut syndrome; Neuropathic pain; Partial epilepsies; Tonic-clonic epilepsy
  • Focus Adverse reactions; Pharmacodynamics; Pharmacokinetics
  • Sponsors GlaxoSmithKline; GSK
  • Most Recent Events

    • 29 Mar 2021 Results of Population PK model analysis from 12 clinical studies: SCB107718, SCB107727, SCB113210, SCB113210, 802HV101, 802HV102, 802HV104, 802HV105, 802HV106, 802HV107, 1014802/202, 1014802/201 and 1014802/205 published in the European Journal of Drug Metabolism and Pharmacokinetics
    • 18 Jun 2008 Status changed from recruiting to completed as reported by ClinicalTrials.gov.
    • 17 Jul 2007 New trial record.

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