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A Phase I, open-label, 2-period, single-sequence, drug interaction study to assess steady-state plasma methadone enantiomer pharmacokinetics following co-administration of methadone QD with fosamprenavir 700mg BID + RTV [ritonavir] 100mg BID in opiate-dependent, HIV seronegative, adult subjects.

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Trial Profile

A Phase I, open-label, 2-period, single-sequence, drug interaction study to assess steady-state plasma methadone enantiomer pharmacokinetics following co-administration of methadone QD with fosamprenavir 700mg BID + RTV [ritonavir] 100mg BID in opiate-dependent, HIV seronegative, adult subjects.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 20 Aug 2023

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At a glance

  • Drugs Fosamprenavir (Primary) ; Methadone; Ritonavir
  • Indications Opioid-related disorders
  • Focus Pharmacokinetics
  • Sponsors GlaxoSmithKline; GSK

    • Most Recent Events

    • 31 Jul 2007 New trial record.

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