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A randomised phase III study to compare arsenic trioxide (ATO) combined to ATRA versus standard ATRA and anthracycline-based chemotherapy (AIDA regimen) for newly diagnosed, non high-risk acute promyelocytic leukaemia

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Trial Profile

A randomised phase III study to compare arsenic trioxide (ATO) combined to ATRA versus standard ATRA and anthracycline-based chemotherapy (AIDA regimen) for newly diagnosed, non high-risk acute promyelocytic leukaemia

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 13 Oct 2022

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At a glance

  • Drugs Arsenic trioxide (Primary) ; Idarubicin; Mercaptopurine; Methotrexate; Methotrexate; Mitoxantrone; Tretinoin
  • Indications Acute promyelocytic leukaemia
  • Focus Therapeutic Use

    • Most Recent Events

    • 31 Dec 2021 Planned End Date changed from 1 Dec 2018 to 1 Jan 2022.
    • 19 Oct 2018 Planned End Date changed from 1 May 2018 to 1 Dec 2018.
    • 21 Mar 2018 The Planned end date (1 May 2018) is the expected follow-up date for patients receiving therapy after the trial is completed.

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