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A phase I, double-blind, placebo-controlled, single-dose, dose-escalation study of the safety, pharmacokinetics, and preliminary efficacy of XOMA 052 in subjects with type 2 diabetes mellitus.

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Trial Profile

A phase I, double-blind, placebo-controlled, single-dose, dose-escalation study of the safety, pharmacokinetics, and preliminary efficacy of XOMA 052 in subjects with type 2 diabetes mellitus.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 03 Oct 2021

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At a glance

  • Drugs Gevokizumab (Primary)
  • Indications Type 2 diabetes mellitus
  • Focus Adverse reactions; Pharmacokinetics; Therapeutic Use
  • Sponsors XOMA
  • Most Recent Events

    • 30 Sep 2009 Status changed from active, no longer recruiting to completed. Phase I trials of XOMA 052 are complete according to a XOMA media release.
    • 14 Jul 2009 Interim results were reported in a Xoma media release; Xoma announced positive results from single and multiple dose subcutaneous arms of the trial; Placebo patients from both US and Sweden Phase I trials included.
    • 09 Jun 2009 Results were presented at the American Diabetes Assocation 69th Annual Scientific Sessions.

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