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Phase 2, Multicenter, Open-Label, Two-Stage Study to Evaluate the Safety and Efficacy of Intra-Arterial Catheter-Directed Alfimeprase for Restoration of Neurologic Function and Rapid Opening of Arteries in Stroke (CARNEROS-1).

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Trial Profile

Phase 2, Multicenter, Open-Label, Two-Stage Study to Evaluate the Safety and Efficacy of Intra-Arterial Catheter-Directed Alfimeprase for Restoration of Neurologic Function and Rapid Opening of Arteries in Stroke (CARNEROS-1).

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 10 Nov 2021

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At a glance

  • Drugs Alfimeprase (Primary)
  • Indications Embolism and thrombosis; Stroke
  • Focus Proof of concept; Therapeutic Use
  • Acronyms CARNEROS-1
  • Sponsors Nuvelo

    • Most Recent Events

    • 05 May 2009 Sponsor, affiliate and lead trial centre (ARCA Biopharma) added as reported by ClinicalTrials.gov.
    • 17 Mar 2008 Status changed from recruiting to discontinued: Nuvelo have decided to terminate their clinical development of alfimeprase after obtaining disappointing efficacy results in the SONOMA-3 trial [see media release 9086453 and profile 700018108].
    • 12 Dec 2007 First patient dosed according to Nuvelo media release.

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