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A double-blind, randomised, placebo-controlled, three-period crossover study to investigate the pharmacodynamic effect of two CRF1 antagonists GSK561679 and GW876008 on meal induced cortisol responses in patients with IBS.

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Trial Profile

A double-blind, randomised, placebo-controlled, three-period crossover study to investigate the pharmacodynamic effect of two CRF1 antagonists GSK561679 and GW876008 on meal induced cortisol responses in patients with IBS.

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 05 Sep 2023

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At a glance

  • Drugs Emicerfont (Primary) ; Verucerfont (Primary)
  • Indications Irritable bowel syndrome
  • Focus Pharmacodynamics; Pharmacogenomic
  • Sponsors GlaxoSmithKline; GSK

    • Most Recent Events

    • 23 Jun 2019 Trial was discontinued in Ireland, according to European Clinical Trials Database record.
    • 18 Jan 2008 Status changed from initiated to discontinued. Updated from ClinicalTrials.gov.
    • 13 Aug 2007 New trial record.

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