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A phase IB, study to investigate the effect of ketoconazole, a CYP3A4 inhibitor, on oral LBH589 [panobinostat] and to assess the efficacy and safety of oral LBH589 in patients with advanced solid tumors

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A phase IB, study to investigate the effect of ketoconazole, a CYP3A4 inhibitor, on oral LBH589 [panobinostat] and to assess the efficacy and safety of oral LBH589 in patients with advanced solid tumors

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 10 Nov 2021

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At a glance

  • Drugs Panobinostat (Primary) ; Ketoconazole
  • Indications Non-Hodgkin's lymphoma; Solid tumours
  • Focus Pharmacokinetics

    • Most Recent Events

    • 12 Apr 2011 Status changed from recruiting to completed as reported by ClinicalTrials.gov.
    • 12 Apr 2011 Actual initiation date changed from Jul 2007 to Sep 2007 as reported by ClinicalTrials.gov.
    • 12 Apr 2011 Actual end date (Apr 2010) added as reported by ClinicalTrials.gov.

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