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Phase II study of combination therapy with 5-AZAcytidine, valproic acid, and all-trans retinoic acid [tretinoin] in patients with myelodysplastic syndromes and other myeloid malignancies who cannot receive intensive chemotherapy

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Trial Profile

Phase II study of combination therapy with 5-AZAcytidine, valproic acid, and all-trans retinoic acid [tretinoin] in patients with myelodysplastic syndromes and other myeloid malignancies who cannot receive intensive chemotherapy

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 02 Nov 2021

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At a glance

  • Drugs Azacitidine (Primary) ; Valproic acid (Primary) ; Tretinoin
  • Indications Myelodysplastic syndromes
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms AZAVATRA
  • Most Recent Events

    • 01 May 2010 Actual end date (May 2010) added as reported by ISRCTN: Current Controlled Trials.
    • 01 May 2010 Status changed from recruiting to completed as reported by ISRCTN: Current Controlled Trials.
    • 16 Aug 2007 New trial record.

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