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A phase 1, randomized, double-blind, dose-escalation cohort study to evaluate the safety, tolerability and pharmacokinetics of a single intravenous infusion of MGAWN1, a neutralizing, humanized, monoclonal antibody (IgG [immunoglobulin] 1K) to West Nile virus, in healthy adults

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Trial Profile

A phase 1, randomized, double-blind, dose-escalation cohort study to evaluate the safety, tolerability and pharmacokinetics of a single intravenous infusion of MGAWN1, a neutralizing, humanized, monoclonal antibody (IgG [immunoglobulin] 1K) to West Nile virus, in healthy adults

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 23 Feb 2022

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At a glance

  • Drugs MGAWN1 (Primary)
  • Indications West Nile virus infections
  • Focus Adverse reactions; Pharmacokinetics
  • Acronyms CP-MGAWN1-01
  • Sponsors MacroGenics
  • Most Recent Events

    • 29 Mar 2010 Results published in Antimicrobial Agents and Chemotherapy.
    • 13 Jul 2009 Status changed from active, no longer recruiting to completed according to Macrogenics media release.
    • 25 Oct 2008 Results presented at ICAAC-IDSA 2008.
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