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A Randomized Multicenter Double-Blind Group-Sequential Study to Evaluate the Efficacy Immunogenicity and Safety of a Single Dose of Merck Staphylococcus Aureus Vaccine (V710) in Adult Patients Scheduled for Cardiothoracic Surgery

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Trial Profile

A Randomized Multicenter Double-Blind Group-Sequential Study to Evaluate the Efficacy Immunogenicity and Safety of a Single Dose of Merck Staphylococcus Aureus Vaccine (V710) in Adult Patients Scheduled for Cardiothoracic Surgery

Status: Discontinued
Phase of Trial: Phase II/III

Latest Information Update: 09 May 2022

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At a glance

  • Drugs V-710 (Primary)
  • Indications Mediastinitis; Staphylococcal infections; Surgical wound infections
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Sponsors Merck Sharp & Dohme

    • Most Recent Events

    • 19 Jun 2019 This trial has been discontinued in France, according to European Clinical Trials Database.
    • 03 Apr 2013 Primary endpoint 'Vaccine-protective-efficacy' has not been met.
    • 03 Apr 2013 Results published in JAMA: the Journal of the American Medical Association.
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