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Prospective, Randomized, Open, Multicentre Study About the Effect of an Empirical Antibiotic Monotherapy With Meropenem (Meronem) Versus a Combination Therapy With Moxifloxacin (Avalox) on Organ Dysfunction in Patients With Severe Sepsis and Septic Shock.

Trial Profile

Prospective, Randomized, Open, Multicentre Study About the Effect of an Empirical Antibiotic Monotherapy With Meropenem (Meronem) Versus a Combination Therapy With Moxifloxacin (Avalox) on Organ Dysfunction in Patients With Severe Sepsis and Septic Shock.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 24 Apr 2014

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At a glance

  • Drugs Meropenem (Primary) ; Moxifloxacin (Primary)
  • Indications Sepsis; Septic shock
  • Focus Therapeutic Use
  • Acronyms MaxSep
  • Most Recent Events

    • 13 Jun 2012 Results published in JAMA: the Journal of the American Medical Association.
    • 13 Jun 2012 Primary endpoint 'Assessment-scale-scores' has not been met.
    • 02 Jul 2010 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.
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