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A Phase Ib, Multi-center, Open-label, Dose-escalation Study of Oral LBH589 When Administered in Combination With Bortezomib in Adult Patients With Multiple Myeloma.

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Trial Profile

A Phase Ib, Multi-center, Open-label, Dose-escalation Study of Oral LBH589 When Administered in Combination With Bortezomib in Adult Patients With Multiple Myeloma.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 21 Dec 2020

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At a glance

  • Drugs Bortezomib (Primary) ; Panobinostat (Primary) ; Dexamethasone
  • Indications Multiple myeloma
  • Focus Adverse reactions
  • Sponsors Novartis
  • Most Recent Events

    • 12 Mar 2014 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov record.
    • 16 Apr 2012 Planned end date changed from 1 Dec 2010 to 1 Dec 2012 as reported by ClinicalTrials.gov.
    • 07 Jun 2011 According to an abstract presented at ASCO, as of 24 January, 24 patients had been enrolled. Stage 1 recruitment has been completed and interim analysis is underway, with Stage 2 anticipated to start soon.

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