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A study to evaluate the efficacy and safety of the combination of aliskiren/ramipril/amlodipine (300/10/10 mg) compared to the combinations of ramipril/amlodipine (10/10 mg) and aliskiren/amlodipine (300/10 mg) in patients with essential hypertension and metabolic syndrome not adequately responsive to amlodipine 10 mg

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A study to evaluate the efficacy and safety of the combination of aliskiren/ramipril/amlodipine (300/10/10 mg) compared to the combinations of ramipril/amlodipine (10/10 mg) and aliskiren/amlodipine (300/10 mg) in patients with essential hypertension and metabolic syndrome not adequately responsive to amlodipine 10 mg

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 10 Nov 2021

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At a glance

  • Drugs Aliskiren (Primary) ; Ramipril (Primary) ; Amlodipine
  • Indications Essential hypertension
  • Focus Therapeutic Use
  • Acronyms ALTO
  • Sponsors Novartis

    • Most Recent Events

    • 12 Apr 2012 Planned number of patients changed from 178 to 846 as reported by European Clinical Trials Database record.
    • 12 Apr 2012 Status changed from discontinued to completed as reported by European Clinical Trials Database record.
    • 23 May 2011 Status changed from active, no longer recruiting to discontinued as reported by ClinicalTrials.gov.

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