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A Randomised, Double-Blind, Placebo Controlled, Parallel-Group, Multicenter Study to Evaluate the Efficacy and Safety of Two Doses of Ocrelizumab in Patients With Active Systemic Lupus Erythematosus

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Trial Profile

A Randomised, Double-Blind, Placebo Controlled, Parallel-Group, Multicenter Study to Evaluate the Efficacy and Safety of Two Doses of Ocrelizumab in Patients With Active Systemic Lupus Erythematosus

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 22 Dec 2021

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At a glance

  • Drugs Ocrelizumab (Primary) ; Immunosuppressants; Prednisone
  • Indications Systemic lupus erythematosus
  • Focus Registrational; Therapeutic Use
  • Acronyms BEGIN
  • Sponsors Genentech; Roche
  • Most Recent Events

    • 26 Jun 2012 Additional locations added as reported by European Clinical Trials Database record.
    • 09 Mar 2010 Trial has been halted since May 2008 due to serious and opportunistic infections signals, as reported by media releases from Roche and Biogen Idec.
    • 09 Mar 2010 Trial has been halted since May 2008 due to serious and opportunistic infections signals, as reported by media releases from Roche and Biogen Idec.
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