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An Open-Label, 12-Month Safety and Efficacy Study of Levodopa - Carbidopa Intestinal Gel in Levodopa-Responsive Subjects With Advanced Parkinson's Disease and Severe Motor-Fluctuations Despite Optimized Treatment With Available Parkinson's Disease Medications

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Trial Profile

An Open-Label, 12-Month Safety and Efficacy Study of Levodopa - Carbidopa Intestinal Gel in Levodopa-Responsive Subjects With Advanced Parkinson's Disease and Severe Motor-Fluctuations Despite Optimized Treatment With Available Parkinson's Disease Medications

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 05 Oct 2021

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At a glance

  • Drugs Levodopa/carbidopa (Primary)
  • Indications Parkinson's disease
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Abbott Laboratories; AbbVie; Solvay Pharmaceuticals B.V.

Most Recent Events

  • 21 Apr 2016 Post-hoc subgroup analysis (n=286) of effect of levodopa-carbidopa intestinal gel on resting tremor in patients were presented at the 68th Annual Meeting of the American Academy of Neurology.
  • 28 Jan 2016 Pooled exploratory post-hoc analysis of 3 trials including this trial and 2 other studies [see CTP 700017544 and 70033178] were published in the Movement Disorders.
  • 18 Jun 2012 Final results were presented at the 16th International Congress of Parkinson's Disease and Movement Disorders.

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