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Comparison of insulin lispro low mixture with insulin glargine when initiating and intensifying insulin therapy as required in patients with type 2 diabetes who have inadequate glycemic control on oral antihyperglycemic medication.

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Trial Profile

Comparison of insulin lispro low mixture with insulin glargine when initiating and intensifying insulin therapy as required in patients with type 2 diabetes who have inadequate glycemic control on oral antihyperglycemic medication.

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 10 Nov 2021

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At a glance

  • Drugs Insulin neutral protamine lispro/insulin lispro (Primary) ; Insulin glargine; Insulin lispro
  • Indications Type 2 diabetes mellitus
  • Focus Therapeutic Use
  • Acronyms PARADIGM
  • Sponsors Eli Lilly and Company

    • Most Recent Events

    • 13 Jun 2017 Results of post hoc analysis evaluating glycemic profiles of lispro Mix25-treated patients, presented at the 77th Annual Scientific Sessions of the American Diabetes Association.
    • 05 Jun 2012 Primary endpoint 'Proportion-of-glycosylated-haemoglobin' has been met according to results published in Diabetic Medicine.
    • 05 Jun 2012 Results published in Diabetic Medicine.

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