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A randomized, double-blind, placebo-controlled, dose ascending, 3-cohort parallel group study to measure the systemic cortisol profile and evaluate the safety, tolerability and pharmacokinetics of GW870086X[GSK-870086], administered as single doses (12mg and 15mg), and repeat doses over 3 days (6mg, 12mg and 15mg) in healthy male subjects.

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Trial Profile

A randomized, double-blind, placebo-controlled, dose ascending, 3-cohort parallel group study to measure the systemic cortisol profile and evaluate the safety, tolerability and pharmacokinetics of GW870086X[GSK-870086], administered as single doses (12mg and 15mg), and repeat doses over 3 days (6mg, 12mg and 15mg) in healthy male subjects.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 28 Jun 2023

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At a glance

  • Drugs GSK 870086 (Primary)
  • Indications Asthma
  • Focus Adverse reactions; Pharmacodynamics
  • Sponsors GlaxoSmithKline; GSK

    • Most Recent Events

    • 15 Oct 2008 Actual start date changed from Oct 2007 to Sep 2007 as reported by Clinicaltrials.gov
    • 31 Mar 2008 Status change from initiated to completed according to clinicaltrials.gov.
    • 07 Nov 2007 New trial record.
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