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A Comparison of Prasugrel and Clopidogrel in Acute Coronary Syndrome Subjects With Unstable Angina/Non-ST-Elevation Myocardial Infarction Who Are Medically Managed

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Trial Profile

A Comparison of Prasugrel and Clopidogrel in Acute Coronary Syndrome Subjects With Unstable Angina/Non-ST-Elevation Myocardial Infarction Who Are Medically Managed

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 08 Aug 2022

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At a glance

  • Drugs Prasugrel (Primary) ; Aspirin; Clopidogrel
  • Indications Acute coronary syndromes; Cardiovascular disorders; Myocardial infarction; Unstable angina pectoris
  • Focus Registrational; Therapeutic Use
  • Acronyms TRILOGY-ACS
  • Sponsors Eli Lilly and Company

    • Most Recent Events

    • 11 Jul 2022 Results assessing cardiovascular outcomes in patients with DM presenting with ACS, stratified by PAD status from 4 randomized post-ACS trials (PLATO, APPRAISE-2, TRILOGY, and TRACE) published in the American Journal of Cardiology.
    • 15 Nov 2021 Results (N=47,474), pooled analysis of data from 4 multicenter randomized trials (APPRAISE-2, PLATO, TRACER and TRILOGY ACS) presented at the American Heart Association Scientific Sessions 2021
    • 14 Jul 2020 Results (N=45011), pooled analysis of data from 4 multicenter randomized trials (APPRAISE-2, PLATO, TRACER and TRILOGY ACS) assessing the association of post discharge bleeding after Acute coronary syndrome with a similar increase in subsequent all cause mortality, published in the Journal of the American College of Cardiology

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