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A multinational, randomized, double-blind study, comparing the efficacy of aflibercept once every 2 weeks versus placebo in patients with metastatic colorectal cancer (MCRC) treated with irinotecan/5-FU combination (FOLFIRI) after failure of an oxaliplatin based regimen

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A multinational, randomized, double-blind study, comparing the efficacy of aflibercept once every 2 weeks versus placebo in patients with metastatic colorectal cancer (MCRC) treated with irinotecan/5-FU combination (FOLFIRI) after failure of an oxaliplatin based regimen

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 05 Jul 2024

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At a glance

  • Drugs Aflibercept (Primary) ; Fluorouracil; Folinic acid; Irinotecan
  • Indications Adenocarcinoma; Colorectal cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms VELOUR
  • Sponsors Sanofi

    • Most Recent Events

    • 04 Jun 2024 Results (n=439) presented at the 60th Annual Meeting of the American Society of Clinical Oncology.
    • 14 Nov 2019 Results of post hoc analysis investigating the effect of plasma growth factor levels on patient outcomes in patients with mCRC treated with aflibercept versus placebo in the VELOUR trial published in the Clinical Cancer Research
    • 21 Jan 2017 Results (n=553) presented at the 2017 Gastrointestinal Cancers Symposium

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