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A Phase III Randomized Controlled Clinical Trial of Carboplatin and Paclitaxel (or Gemcitabine) Alone or in Combination With Bevacizumab (NSC #704865) Followed by Bevacizumab and Secondary Cytoreductive Surgery in Platinum-Sensitive, Recurrent Ovarian, Peritoneal Primary and Fallopian Tube Cancer. NCI-Supplied Agents: Bevacizumab (NSC #704865)

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Trial Profile

A Phase III Randomized Controlled Clinical Trial of Carboplatin and Paclitaxel (or Gemcitabine) Alone or in Combination With Bevacizumab (NSC #704865) Followed by Bevacizumab and Secondary Cytoreductive Surgery in Platinum-Sensitive, Recurrent Ovarian, Peritoneal Primary and Fallopian Tube Cancer. NCI-Supplied Agents: Bevacizumab (NSC #704865)

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 08 May 2024

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At a glance

  • Drugs Bevacizumab (Primary) ; Carboplatin; Docetaxel; Gemcitabine; Paclitaxel
  • Indications Adenocarcinoma; Carcinoma; Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • Focus Therapeutic Use
  • Most Recent Events

    • 11 Jan 2021 Number of treatment arms has been decreased from 8 to 4, by removing arms III, IV, VI and VIII and modifying the remaining 4 arms.
    • 13 Aug 2019 Planned primary completion date changed from 15 Mar 2019 to 19 Dec 2019.
    • 05 Jun 2018 Results (n=215) presented at the 54th Annual Meeting of the American Society of Clinical Oncology.

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