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Phase I/II Study of Autologous Tumor Cell Vaccination Using Metronomic Cyclophosphamide, 3-Dimensional Conformal Radiotherapy, Intra/Peri-Tumor Injection of Poly ICLC With Trans-Hepatic Arterial Embolization Followed by Poly ICLC Boosting in Patients With Unresectable, Recurrent, or Metastatic Cancers in the Liver (Hepatoma, Cholangiocarcinoma, Neuroendocrine, Breast, Colon, Gastric, and Esophageal Cancer).

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Trial Profile

Phase I/II Study of Autologous Tumor Cell Vaccination Using Metronomic Cyclophosphamide, 3-Dimensional Conformal Radiotherapy, Intra/Peri-Tumor Injection of Poly ICLC With Trans-Hepatic Arterial Embolization Followed by Poly ICLC Boosting in Patients With Unresectable, Recurrent, or Metastatic Cancers in the Liver (Hepatoma, Cholangiocarcinoma, Neuroendocrine, Breast, Colon, Gastric, and Esophageal Cancer).

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 19 Aug 2015

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At a glance

  • Drugs Poly ICLC (Primary) ; Poly ICLC (Primary) ; Cyclophosphamide
  • Indications Advanced breast cancer; Cholangiocarcinoma; Colon cancer; Gastric cancer; Liver cancer; Liver metastases; Malignant melanoma; Neuroendocrine carcinoma; Oesophageal cancer; Ovarian cancer; Pancreatic cancer
  • Focus Adverse reactions

    • Most Recent Events

    • 11 Jan 2014 Endpoints amended as reported by ClinicalTrials.gov
    • 11 Jan 2014 Planned End Date changed from 1 Oct 2009 to 1 Jul 2014 as reported by ClinicalTrials.gov
    • 30 Jun 2009 New source identified and integrated (New Jersey Cancer Trial Connect).

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