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A phase II study incorporating bone marrow microenvironment (ME) - co-targeting bortezomib into tandem melphalan-based autotransplants with DTPACE [cisplatin + doxorubicin + cyclophosphamide + etoposide] for induction/consolidation and thalidomide + dexamethasone for maintenance

Trial Profile

A phase II study incorporating bone marrow microenvironment (ME) - co-targeting bortezomib into tandem melphalan-based autotransplants with DTPACE [cisplatin + doxorubicin + cyclophosphamide + etoposide] for induction/consolidation and thalidomide + dexamethasone for maintenance

Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 26 Sep 2018

At a glance

  • Drugs Bortezomib (Primary) ; Cisplatin; Cyclophosphamide; Dexamethasone; Doxorubicin; Etoposide; Melphalan; Thalidomide
  • Indications Multiple myeloma
  • Focus Therapeutic Use
  • Acronyms TT-IIIB
  • Most Recent Events

    • 18 Sep 2018 Planned End Date changed from 1 Aug 2018 to 1 Aug 2019.
    • 18 Sep 2018 Planned primary completion date changed from 1 Aug 2018 to 1 Aug 2019.
    • 05 Sep 2017 Planned End Date changed from 1 Aug 2017 to 1 Aug 2018.
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