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A Phase IIa Study of AdV-tk + Valacyclovir Gene Therapy in Combination With Standard Radiation Therapy for Malignant Gliomas

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Trial Profile

A Phase IIa Study of AdV-tk + Valacyclovir Gene Therapy in Combination With Standard Radiation Therapy for Malignant Gliomas

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 05 Apr 2024

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At a glance

  • Drugs Aglatimagene besadenovec (Primary) ; Temozolomide; Valaciclovir
  • Indications Glioma
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Candel Therapeutics

    • Most Recent Events

    • 21 Mar 2019 Results published in the Candel Therapeutics Media Release
    • 06 Feb 2017 Status changed from active, no longer recruiting to completed.
    • 03 Mar 2016 Therapeutic use has been added to Trial focus; Secondary outcome of Overall survival has been made primary outcome and time frame has been extended from 24 months to 5 years as per ClinicalTrials.gov record.

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