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Prospective, randomized trial of rapamycin [sirolimus]- and zotarolimus-eluting stents for the reduction of coronary restenosis

Trial Profile

Prospective, randomized trial of rapamycin [sirolimus]- and zotarolimus-eluting stents for the reduction of coronary restenosis

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 13 Jul 2022

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At a glance

  • Drugs Probucol (Primary) ; Sirolimus (Primary) ; Zotarolimus
  • Indications Coronary artery disease; Coronary artery restenosis; Myocardial infarction; Myocardial ischaemia; Stent thrombosis
  • Focus Therapeutic Use
  • Acronyms ISAR-TEST-5
  • Most Recent Events

    • 01 Jul 2022 Results (n=4953) of a post-hoc analysis assessing target and non-target vessel related events at 10 years from two clinical studies: NCT00598676 and NCT00598533 published in the Clinical Research in Cardiology
    • 14 Jul 2020 Results published in the Journal of the American College of Cardiology
    • 18 Nov 2019 Results assessing very long term outcomes of patients treated with either permanent polymer-based zotarolimus-eluting stent and polymer-free sirolimus- and probucol-eluting stent were presented at the American Heart Association Scientific Sessions 2019
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