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A comparative study of the antiviral efficacy and safety of entecavir plus tenofovir versus adefovir added to continuing lamivudine in adults with lamivudine- resistant chronic hepatitis B virus infection.

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Trial Profile

A comparative study of the antiviral efficacy and safety of entecavir plus tenofovir versus adefovir added to continuing lamivudine in adults with lamivudine- resistant chronic hepatitis B virus infection.

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 10 Nov 2021

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At a glance

  • Drugs Adefovir dipivoxil (Primary) ; Entecavir (Primary) ; Lamivudine; Tenofovir disoproxil fumarate
  • Indications Hepatitis B
  • Focus Therapeutic Use
  • Sponsors Bristol-Myers Squibb
  • Most Recent Events

    • 14 Jul 2012 Planned number of patients changed from 84 to 105 as reported by European Clinical Trials Database.
    • 25 Nov 2008 Status changed from recruiting to discontinued, as business objectives have changed, reported by ClinicalTrials.gov.
    • 28 Sep 2008 Planned end date changed from 1 Mar 2012 to 1 Apr 2012 as reported by ClinicalTrials.gov.

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