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A Randomised, Double-Blind, Placebo Controlled, Parallel-Group, Multicenter Study to Evaluate the Efficacy and Safety of Two Doses of Ocrelizumab in Patients With WHO or ISN Class III or IV Nephritis Due to Systemic Lupus Erythematosus

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Trial Profile

A Randomised, Double-Blind, Placebo Controlled, Parallel-Group, Multicenter Study to Evaluate the Efficacy and Safety of Two Doses of Ocrelizumab in Patients With WHO or ISN Class III or IV Nephritis Due to Systemic Lupus Erythematosus

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 01 Jan 2024

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At a glance

  • Drugs Ocrelizumab (Primary) ; Corticosteroids; Corticosteroids; Cyclophosphamide; Mycophenolate mofetil
  • Indications Lupus nephritis
  • Focus Registrational; Therapeutic Use
  • Acronyms BELONG
  • Sponsors Genentech

    • Most Recent Events

    • 15 Nov 2023 Initial post hoc analysis of patients in the control arms of the LUNAR and BELONG trial presented at the ACR Convergence 2023
    • 01 Mar 2023 Results comparing differences between B-cell depletion in lupus nephritis patient populations who received rituximab (LUNAR), ocrelizumab (BELONG), or obinutuzumab (NOBILITY), published in the Clinical Immunology
    • 20 Dec 2021 This trial has been completed in Hungary, according to European Clinical Trials Database record.

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