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CIRG (TRIO) 011/NSABP B-44-I / B020906: A Multicenter Phase III Randomized Trial of Adjuvant Therapy for Patients with HER2-Positive Node-Positive or High Risk Node-Negative Breast Cancer Comparing Chemotherapy Plus Trastuzumab with Chemotherapy Plus Trastuzumab Plus Bevacizumab

Trial Profile

CIRG (TRIO) 011/NSABP B-44-I / B020906: A Multicenter Phase III Randomized Trial of Adjuvant Therapy for Patients with HER2-Positive Node-Positive or High Risk Node-Negative Breast Cancer Comparing Chemotherapy Plus Trastuzumab with Chemotherapy Plus Trastuzumab Plus Bevacizumab

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 19 Feb 2024

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At a glance

  • Drugs Bevacizumab (Primary) ; Trastuzumab (Primary) ; Carboplatin; Cyclophosphamide; Docetaxel; Epirubicin; Fluorouracil
  • Indications Adenocarcinoma; Early breast cancer; HER2 positive breast cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms BETH
  • Sponsors Roche

Most Recent Events

  • 19 Jan 2022 This trial has been completed in Slovakia, according to European Clinical Trials Database record.
  • 16 Dec 2021 This trial has been completed in France, according to European Clinical Trials Database record.
  • 05 Oct 2021 This trial has been completed in Spain (End Date: 17 Apr 2014), according to European Clinical Trials Database record.

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