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A Phase I Dose Escalation Study of SGN-35 Alone and in Combination With Gemcitabine in Patients With Relapsed/Refractory CD30-Positive Hematologic Malignancies.

Trial Profile

A Phase I Dose Escalation Study of SGN-35 Alone and in Combination With Gemcitabine in Patients With Relapsed/Refractory CD30-Positive Hematologic Malignancies.

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 28 Oct 2020

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At a glance

  • Drugs Brentuximab vedotin (Primary) ; Gemcitabine
  • Indications Haematological malignancies; Hodgkin's disease
  • Focus Adverse reactions; Pharmacokinetics
  • Sponsors Seagen
  • Most Recent Events

    • 29 Jan 2018 Results (n=380) of pooled data from six trials assessing population pk and exposure-response relationships for the antibody-drug conjugate brentuximab vedotin in ctcl patients, were published in the Clinical Pharmacology and Therapeutics.
    • 12 Jun 2011 Retrospective analysis of two phase I trials, including this trial, presented at the16th Congress of the European Haematology Association (EHA-2011).
    • 05 May 2010 Actual end date (Apr 2010) and actual number of patients (44) added as reported by ClinicalTrials.gov.

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