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A randomized trial investigating the role of FOLFOX-4 [fluorouracil + fluorouracil + folinic acid] regimen duration (3 versus 6 months) and bevacizumab as adjuvant therapy for patients with stage II/III colon cancer

Trial Profile

A randomized trial investigating the role of FOLFOX-4 [fluorouracil + fluorouracil + folinic acid] regimen duration (3 versus 6 months) and bevacizumab as adjuvant therapy for patients with stage II/III colon cancer

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 17 Jul 2021

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At a glance

  • Drugs Capecitabine (Primary) ; Fluorouracil (Primary) ; Folinic acid (Primary) ; Oxaliplatin (Primary) ; Bevacizumab
  • Indications Adenocarcinoma; Colon cancer
  • Focus Therapeutic Use
  • Acronyms TOSCA
  • Most Recent Events

    • 08 Jun 2021 Results from 6 randomised trials NCT00749450, NCT00646607, NCT01150045, NCT00958737) in the IDEA database used to compare characteristics, tx adherence, and adverse events presented at the 57th Annual Meeting of the American Society of Clinical Oncology.
    • 18 Mar 2021 Results (n=2360) of post hoc analysis published in the European Journal of Cancer
    • 12 Oct 2020 Results published in the Annals of Oncology

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