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Study to Evaluate the Exposure of Rifabutin Administered in an Alternate Regimen in Combination With Atazanavir and Ritonavir Healthy Subjects.

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Trial Profile

Study to Evaluate the Exposure of Rifabutin Administered in an Alternate Regimen in Combination With Atazanavir and Ritonavir Healthy Subjects.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 10 Nov 2021

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At a glance

  • Drugs Rifabutin (Primary) ; Atazanavir; Ritonavir
  • Indications HIV-1 infections; Mycobacterium avium complex infections; Tuberculosis
  • Focus Adverse reactions; Pharmacokinetics
  • Sponsors Bristol-Myers Squibb

    • Most Recent Events

    • 28 Jun 2011 The study was stopped due to severe declines in neutrophil counts that were reported in more patients who received combination treatment.
    • 28 Jun 2011 Results published in the Journal of Antimicrobial Chemotherapy.
    • 01 Oct 2008 Actual patient number changed from 84 to 33 as reported by ClinicalTrials.gov.

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