An Open-Label, Multicenter, Phase 1 Dose Escalation Study to Evaluate Safety, Tolerability and Anti-tumor Activity of Systemic Buthionine Sulfoximine (BSO) in Combination With Normothermic Isolated Limb Infusion of Melphalan in Subjects With Locally Advanced In-Transit Malignant Melanoma.
Latest Information Update: 18 Sep 2021
At a glance
- Drugs Melphalan (Primary) ; Buthionine sulfoximine
- Indications Malignant melanoma
- Focus Adverse reactions
- 13 Mar 2015 Biomarkers information updated
- 14 Mar 2013 Status changed from active, no longer recruiting to withdrawn prior to recruitment as reported by ClinicalTrials.gov.
- 13 Dec 2011 Additional lead trial centre identified as reported by ClinicalTrials.gov.