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A Dose-Escalation, Randomized Phase I/II Trial of Zalutumumab - a Human Monoclonal Anti-EGF Receptor Antibody - With or Without Irinotecan Chemotherapy in Cetuximab Refractory Colorectal Cancer Patients Who Have Failed Standard Chemotherapy and Progressed During or Within 3 Months of Stopping Cetuximab-Based Therapy.

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A Dose-Escalation, Randomized Phase I/II Trial of Zalutumumab - a Human Monoclonal Anti-EGF Receptor Antibody - With or Without Irinotecan Chemotherapy in Cetuximab Refractory Colorectal Cancer Patients Who Have Failed Standard Chemotherapy and Progressed During or Within 3 Months of Stopping Cetuximab-Based Therapy.

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 19 Jul 2023

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At a glance

  • Drugs Zalutumumab (Primary) ; Irinotecan
  • Indications Colorectal cancer
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Genmab

    • Most Recent Events

    • 22 Dec 2011 Actual patient number is 9 according to ClinicalTrials.gov.
    • 05 Nov 2008 Status changed from recruiting to discontinued, based on information from ClinicalTrials.gov.
    • 05 Nov 2008 Planned end date changed from 1 Feb 2010 to 1 Apr 2009, based on information from ClinicalTrials.gov.

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