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Phase 2 Study of Intravenous Administration of a Wild-Type Reovirus (REOLYSIN) in Combination With Paclitaxel and Carboplatin in Patients With Platinum-Refractory Metastatic and/or Recurrent Squamous Cell Carcinoma of the Head and Neck.

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Trial Profile

Phase 2 Study of Intravenous Administration of a Wild-Type Reovirus (REOLYSIN) in Combination With Paclitaxel and Carboplatin in Patients With Platinum-Refractory Metastatic and/or Recurrent Squamous Cell Carcinoma of the Head and Neck.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 12 Oct 2017

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At a glance

  • Drugs Pelareorep (Primary) ; Carboplatin; Paclitaxel
  • Indications Head and neck cancer
  • Focus Registrational; Therapeutic Use
  • Sponsors Oncolytics Biotech

Most Recent Events

  • 12 Sep 2017 Results (n=563) of pooled data from eight trial (NCI-GOG 0186H, NCI-8601, NCIC-CTG IND.213, REO011, REO015, REO016, REO018 and REO021) assessing the safety and tolerability of intravenous pelareorep in combination with chemotherapy, were presented at the 42nd European Society for Medical Oncology Congress.
  • 03 Nov 2014 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov record.
  • 09 Aug 2011 Planned end date changed from 1 Oct 2011 to 1 Jan 2012 as reported by ClinicalTrials.gov.

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